Panadol Migraine For Severe Migraine And Headaches, 24 Tablets

Panadol Migraine contains the three-ingredient combination of Paracetamol (500mg), Aspirin (500mg), and Caffeine (65mg) that clinical research has established as more effective for migraine relief than either analgesic alone. Caffeine acts as an adjuvant in this combination - it constricts the dilated cerebral blood vessels that contribute to migraine pain, enhances the absorption of both Paracetamol and Aspirin from the gastrointestinal tract, and has an independent analgesic contribution. This triple combination is one of the few OTC migraine treatments with a genuine evidence base for migraine-specific efficacy.

Specs

• Active ingredients: Paracetamol 500mg, Aspirin (ASA) 500mg, Caffeine 65mg per tablet
• Form: Tablets
• Pack size: 24 tablets
• Indication: Migraine with or without aura, severe headache
• Suitable for: Adults 18 years and over

Benefits

• The triple combination of Paracetamol, Aspirin, and Caffeine has been shown in multiple randomized controlled trials to provide superior migraine relief compared to either analgesic alone at the same doses, making it a specifically better choice for migraine than a standard paracetamol or aspirin tablet
• Aspirin (acetylsalicylic acid) is an anti-inflammatory NSAID that addresses the neurogenic inflammation component of migraine pathophysiology that paracetamol alone cannot treat
• Caffeine causes vasoconstriction of the dilated cranial blood vessels that mediate the throbbing pain of migraine, addressing the vascular component directly while enhancing the absorption and CNS penetration of the co-formulated analgesics by approximately 40%
• The combination works best when taken as early as possible at the onset of a migraine episode, before the pain has fully escalated - a key practical instruction that significantly affects treatment efficacy
• The 24-tablet count is appropriate for episodic migraine management without encouraging overuse - medication overuse headache (MOH) is a real risk with frequent analgesic use, and patients should not use this product on more than 10 days per month

How to Use

• Take at the first sign of a migraine - do not wait until the pain has fully developed
• Adults 18 years and over: take 2 tablets with a full glass of water
• Do not exceed 2 tablets per migraine episode
• Do not use more than twice in 24 hours
• Do not use on more than 10 days per month - frequent use can cause medication overuse headache
• Lie down in a dark, quiet room after taking if possible - this enhances the analgesic effect
• Not suitable for people with aspirin allergy, bleeding disorders, kidney disease, peptic ulcers, or those taking blood thinners
• Not suitable during pregnancy - particularly in the third trimester