Nexium Tablet 14s x 20 mg

Nexium 20mg contains Esomeprazole at the standard starting and maintenance dose for the management of gastro-oesophageal reflux disease (GERD), heartburn, and acid-related conditions. The 20mg dose is appropriate for most adults with symptomatic GERD, erosive oesophagitis grade A and B, and for maintenance therapy after healing of more severe oesophagitis. It provides the pharmacological advantage of Esomeprazole's more consistent bioavailability over racemic Omeprazole at a dose that balances efficacy with the minimum necessary PPI exposure.

Specs

• Active ingredient: Esomeprazole Magnesium 20mg
• Drug class: Proton Pump Inhibitor (PPI)
• Form: Enteric-coated tablets
• Pack size: 14 tablets
• Dosing: Once daily - 30 to 60 minutes before breakfast
• Action: Sustained gastric acid suppression for up to 24 hours

Benefits

• Esomeprazole's S-isomer formulation provides more predictable plasma concentrations and acid suppression compared to racemic Omeprazole, with less patient-to-patient variability due to reduced CYP2C19-dependent first-pass metabolism
• Once-daily dosing at 20mg provides sustained acid suppression covering both daytime meal-stimulated acid secretion and the nocturnal acid secretion that is particularly problematic in GERD patients with night symptoms
• The 14-tablet pack provides a standard 2-week assessment course that is appropriate for evaluating the response to PPI therapy for new-onset reflux symptoms before deciding on further treatment
• At 20mg, Nexium is appropriate for both treatment of active GERD symptoms and as long-term maintenance therapy to prevent relapse after healing of erosive oesophagitis - the most common indication for ongoing PPI use
• Nexium's enteric coating ensures the Esomeprazole granules reach the small intestine intact before dissolving, protecting the acid-labile drug from gastric acid destruction and ensuring consistent bioavailability

How to Use

• Swallow whole with water - do not crush or chew
• Take 30 to 60 minutes before breakfast for maximum efficacy
• Standard adult dose: 20mg once daily for the prescribed duration
• For heartburn management: typical course is 2 to 4 weeks
• For GERD maintenance: continue as directed by physician, typically at the lowest effective dose
• If difficulty swallowing, the tablet can be dispersed in a glass of water (without crushing) - swallow the dispersed granules immediately without chewing
• Consult physician before stopping long-term PPI treatment