Diane 35 Tablets, 21 Tablets

Diane-35 contains Cyproterone Acetate 2mg and Ethinylestradiol 0.035mg in a combined oral contraceptive formulation that is unique in having both contraceptive efficacy and specific anti-androgenic activity. Cyproterone Acetate is a progestogen with potent anti-androgen properties that competitively blocks androgen receptors, reducing the sebum production and hair follicle response to androgens that cause acne and hirsutism. Diane-35 is prescribed for women with androgen-dependent conditions where both contraception and anti-androgen treatment are clinically indicated.

Specs

• Active ingredients: Cyproterone Acetate 2mg, Ethinylestradiol 0.035mg per tablet
• Drug class: Combined oral contraceptive with anti-androgenic progestogen
• Form: Film-coated tablets
• Pack size: 21 tablets
• Indications: Contraception + androgen-dependent acne + hirsutism
• Prescription: Required

Benefits

• Cyproterone Acetate's anti-androgenic mechanism reduces sebum production and normalizes the hair follicle response to androgens - addressing the root hormonal cause of androgenic acne rather than just surface management, producing significant improvement in acne severity over 3 to 6 months of treatment
• Simultaneous contraceptive protection means women requiring anti-androgen therapy for acne or hirsutism do not need a separate contraceptive method, simplifying their treatment regimen
• Cycle regulation provides predictable withdrawal bleeds during the pill-free interval, with most patients experiencing lighter, less painful, and more regular menstruation than before treatment
• Ethinylestradiol's oestrogen component contributes to the contraceptive effect and moderates the androgenic action of Cyproterone Acetate with the balanced oestrogen-progestogen ratio that characterizes well-tolerated combined pills
• Diane-35 has a well-established clinical evidence base for its anti-androgen effects in androgenic acne and hirsutism, making it a recognized dermatological and gynaecological treatment option

How to Use

• Take as prescribed by your physician
• Take 1 tablet daily at the same time for 21 consecutive days
• Follow the direction of the arrows on the blister pack
• After the 21 active tablets, take a 7-day pill-free break - a withdrawal bleed occurs during this period
• Start the next pack immediately after the 7-day break
• Read the full patient information leaflet before starting - Diane-35 has specific contraindications and monitoring requirements
• Not for use as contraception alone where anti-androgenic treatment is not clinically indicated
• Do not use during pregnancy - perform a pregnancy test if in doubt